Here’s a fun one from the Christmas episode (gotta love Joe and his enthusiasm!)
Joe: YEAH! Alright, let’s go wassail!!
A few from the latest season… all from Peter.
Louis: “Peter, are you gay?!”
Peter: high pitch voice “Guiltyyyyyyyyyyyyyyyyyyyyyyyyyyyyyyyyyyyyyyyyyyyyyyyyyy!”
Peter: (to Brian) “Sometimes… I don’t believe I know you.”
Peter: (After watching someone on TV) “Good for you… good for you.”
They’re my favourite because of Seth McFarlane’s delivery.
Tom Cruise: You can’t catch me, gay thoughts!
Lois: Please… we can’t take any more schtick.
Lois: Peter, if you shock me, I swear to God, I’m gonna leave you.
Brian: “Now insert Rod Support A into Slot B”. And if you say ‘that’s what she said’ one more time, I’m gonna pop you.
Dr. Hartman: Hmm, 29 lbs; that’s big for your age.
Stewie: Well, forgive me for not being one of those anorexic babies from the diaper commercials.
Lois: I am very upset with you right now.
Peter: Okay, so I tried on your bra. The fellas were putting on a show. I didn’t think I’d make a good Gigi either, but God help me, I was flattered.
Peter: I don’t know where he went. I just asked him to buy me some peanuts and cracker jacks.
Brian: I don’t care if he ever gets back. (beat) I wasn’t being cute; I really hope he’s dead.
Peter- “Ten die in train de-railment, OMH Louis, that is morbidly obese.”
Peter- Common’ Louis, when have we even miscommunicated?
FLASHBACK Peter and Louis standing at a sunset
Louis- I love you Peter
Peter- Ah, about a quarter past 4. hahaha
Lois: Peter you are so immature! Sometimes it feels like i’ve married a child!
Peter: Oh yeah Lois? If Im a child you know what that makes you? a pedophile!
XD serious ownage there!
ROAD HOUSE!
House. Roadhouse. 
Peter: Darn government, won’t let me build a pool on my own land. And after my grandfather helped create one of this country’s most beloved cartoon characters.
Animator: OK, we’ve narrowed it down to two possible names. All in favor of Bugs Bunny?
(everybody except Peter’s grandfather raises their hand)
Animator: And, all in favor of Efrum The R______ Rabbit?
(Peter’s grandfather raises his hand)
I didn’t know if that word was appropiate here, so I censored it.
Peter: I am so glad Brian brought us out here, Lois. He’s a real pal, you know that?
Lois: Well, it’s actually Brian I need to talk to you about.
Peter: Boy, he’s a hell of a guy, isn’t he? He’s the one guy I know I can trust.
Lois: Brian tried to have sex with me.
Peter: …Was he bigger than me?
and,
Rebel: I think we’re doomed!
Jim: Nah. Unless they’ve got any big, giant robot camels, I think we’re OK.
Rebel: Ah, Jim… robot camels.
LMAO I love that scene!
Peter: “Have you not heard? It was my understanding that everyone had heard”
I don’t have one, but here’s a quote I liked from The Simpsons Game:
Matt Groening: “Behold your creator! The greatest visionary in television animation!”
Homer: “Seth MacFarlane?”
Matt Groening: disgusted grunt